Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608088 | 0.94 | NPSR1 (0.45) | NPSR1ALDH1A1HSD11B1LMNAABL1 | |
| SCHEMBL5608188 | 0.91 | ALDH1A1 (0.43) | NPSR1ALDH1A1HSD11B1LMNAABL1 | |
| SCHEMBL5608256 | 0.84 | MEN1 (0.40) | NPSR1ALDH1A1HSD11B1LMNAABL1 | |
| SCHEMBL5351544 | 0.83 | HSD11B1 (0.40) | NPSR1ALDH1A1HSD11B1LMNASMN1; SMN2 | |
| SCHEMBL6559746 | 0.80 | HSD11B1 (0.40) | NPSR1ALDH1A1HSD11B1POLBMEN1 | |
| SCHEMBL5608298 | 0.80 | ALDH1A1 (0.59) | NPSR1ALDH1A1HSD11B1LMNAABL1 | |
| SCHEMBL7455720 | 0.79 | NPSR1 (0.48) | NPSR1ALDH1A1HSD11B1ABL1TSHR | |
| SCHEMBL19357068 | 0.78 | LMNA (0.49) | NPSR1ALDH1A1HSD11B1LMNAPOLB | |
| SCHEMBL21262840 | 0.77 | NPSR1 (0.38) | NPSR1ALDH1A1HSD11B1LMNAABL1 | |
| SCHEMBL7733822 | 0.77 | ALDH1A1 (0.37) | NPSR1ALDH1A1HSD11B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990634-B1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | DAICEL CHEM (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-6429314-B1 | USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| EP-0990634-A1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | Daicel Chemical Industries, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |