Ether

Ether

SCHEMBL5610312

CCC(O)OC(=O)c1ccccc1C(=O)OC.CCOCC

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.45
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 3/20 0.44
CFTR P13569 1/20 0.44
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 5/20 0.42
POLB P06746 2/20 0.42
ATM Q13315 1/20 0.42
GAA P10253 1/20 0.42
GLA P06280 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873754 0.94 TSHR (0.50) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL1513963 0.87 TSHR (0.53) TSHRLMNAALDH1A1HSD17B10KMT2A
SCHEMBL10591636 0.84 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10KDM4E
SCHEMBL28699777 0.83 TSHR (0.70) TSHRLMNAALDH1A1HSD17B10KDM4E
SCHEMBL1513969 0.81 ALDH1A1 (0.56) TSHRLMNAALDH1A1HSD17B10KMT2A
SCHEMBL27637585 0.78 SMN1; SMN2 (0.48) TSHRLMNAALDH1A1HSD17B10KMT2A
SCHEMBL27583153 0.78 UTS2R (0.48) TSHRLMNAALDH1A1HSD17B10KMT2A
SCHEMBL28362466 0.78 LMNA (0.55) TSHRLMNAALDH1A1HSD17B10KMT2A
Ether SCHEMBL4958226 0.77 ALDH1A1 (0.56) TSHRLMNAALDH1A1HSD17B10KMT2A
SCHEMBL3110030 0.76 ALDH1A1 (0.60) TSHRALDH1A1HSD17B10CFTRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101453990-B Bupropion controllable release formulations and manufacturing process thereof BIOKEY INC 2015-05-13 CN claimed
CN-103945832-A A composition, device and method for delayed and sustained release of brain energy molecules JACKS HEALTH TECHNOLOGIES LLC 2014-07-23 CN claimed
US-20230338371-A1 PHARMACEUTICAL COMPOSITIONS OF PROTAC COMPOUNDS AND USES THEREOF Shenzhen Pharmacin Co., Ltd. (CN) 2023-10-26 US disclosed
WO-2023179777-A1 PHARMACEUTICAL COMPOSITIONS OF PROTAC COMPOUNDS AND USES THEREOF Shenzhen Pharmacin Co., Ltd. (CN) 2023-09-28 WO disclosed
WO-2023179774-A1 AMORPHOUS SOLID DISPERSIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Shenzhen Pharmacin Co., Ltd. (CN) 2023-09-28 WO disclosed
US-9387190-B2 Sustained release of topical anesthetics UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2016-07-12 US disclosed
US-20150297550-A1 SUSTAINED RELEASE OF TOPICAL ANESTHETICS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2015-10-22 US disclosed
EP-2914258-A1 SUSTAINED RELEASE OF TOPICAL ANESTHETICS University Of Kentucky Research Foundation (US) 2015-09-09 EP disclosed
CN-103945832-A A composition, device and method for delayed and sustained release of brain energy molecules JACKS HEALTH TECHNOLOGIES LLC 2014-07-23 CN disclosed
WO-2014071203-A1 SUSTAINED RELEASE OF TOPICAL ANESTHETICS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2014-05-08 WO disclosed
EP-1501521-B1 LONG ACTING COMPOSITIONS COMPRISING ZIDOVUDINE AND/OR LAMIVUDINE LUPIN LTD (IN) 2007-05-02 EP disclosed
US-6462030-B1 MICROBIOCIDES TO MYCOPLASMA HOMINIS, MYCOPLASMA CAPRICOLUM, MOBILUNCUS CURTISII AND PREVOTELLA CORPORIS NEW YORK BLOOD CENTER, INC. 2002-10-08 US disclosed
US-20020127276-A1 Biodegradable microbicidal vaginal barrier device NEW YORK BLOOD CENTER, INC. 2002-09-12 US disclosed
US-20020076430-A1 Biodegradable microbicidal vaginal barrier device NEW YORK BLOOD CENTER, INC. 2002-06-20 US disclosed
WO-2002036055-A1 BIODEGRADABLE MICROBICIDAL VAGINAL BARRIER DEVICE NEW YORK BLOOD CENTER, INC. (US) 2002-05-10 WO disclosed
WO-2001005377-A1 METHOD FOR INACTIVATING BACTERIA ASSOCIATED WITH BACTERIAL VAGINOSIS USING CELLULOSE ACETATE PHTHALATE AND/OR HYDROXYPROPYL METHYLCELLULOSE PHTHALATE NEW YORK BLOOD CENTER, INC. (US) 2001-01-25 WO disclosed
US-6165493-A \"Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections\ NEW YORK BLOOD CENTER, INC. (US) 2000-12-26 US disclosed
EP-1030547-A1 METHODS FOR PREVENTING AND TREATING BACTERIAL INFECTIONS USING CELLULOSE ACETATE PHTHALATE OR HYDROXYPROPYL METHYLCELLULOSE PHTHALATE EXCIPIENTS New York Blood Center, Inc. (US) 2000-08-30 EP disclosed
US-5985313-A Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients NEW YORK BLOOD CENTER, INC. (US) 1999-11-16 US disclosed
WO-1999020098-A1 METHODS FOR PREVENTING AND TREATING BACTERIAL INFECTIONS USING CELLULOSE ACETATE PHTHALATE OR HYDROXYPROPYL METHYLCELLULOSE PHTHALATE EXCIPIENTS NEW YORK BLOOD CENTER, INC. (US) 1999-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338371-A1 PHARMACEUTICAL COMPOSITIONS OF PROTAC COMPOUNDS AND USES THEREOF ADRM1, PSMC1, UBE3C TSHR 3812/4885LMNA 1165/4885ALDH1A1 4530/4885
US-20020127276-A1 Biodegradable microbicidal vaginal barrier device MIF, MGAM, HPD TSHR 4881/4885LMNA 3868/4885ALDH1A1 587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.