Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4062480 | 0.78 | BCHE (0.30) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6457215 | 0.77 | HTR6 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7601225 | 0.77 | ALDH1A1 (0.33) | MAPK1NPSR1BCHEACHE | |
| Hydrochloric Acid SCHEMBL8414418 | 0.73 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7193390 | 0.71 | CYP1A2 (0.37) | — | |
| Bromide SCHEMBL7943471 | 0.71 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4056251 | 0.71 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4323900 | 0.69 | JAK2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4313985 | 0.69 | — | — | |
| SCHEMBL6256373 | 0.69 | CYP2D6 (0.37) | MAPK1NPSR1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149386-A1 | Catalyst system for olefin polymerization | EQUISTAR CHEMICALS, LP | 2007-06-28 | — | — | US | disclosed |