SCHEMBL7548703

SCHEMBL7548703

CCOC(=O)Sn1ccc(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.43
PKM P14618 1/20 0.43
DUT P33316 5/20 0.43
EP300 Q09472 2/20 0.41
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546865 0.75 CRBN (0.44) CRBNPKMDUTALDH1A1LMNA
SCHEMBL665845 0.73 CRBN (0.54) CRBNPKMDUTALDH1A1LMNA
SCHEMBL6937491 0.72 L3MBTL1 (0.55) PKMDUTEP300ALDH1A1LMNA
SCHEMBL8656959 0.72 CRBN (0.48) CRBNPKMDUTALDH1A1LMNA
SCHEMBL5613633 0.70 ALDH1A1 (0.40) CRBNPKMDUTALDH1A1LMNA
SCHEMBL954608 0.69 CRBN (0.46) CRBNPKMDUT
SCHEMBL27578551 0.69 CRBN (0.46) CRBNPKMDUTALDH1A1LMNA
SCHEMBL28545721 0.69 CRBN (0.46) CRBNDUT
SCHEMBL8064655 0.68 PKM (0.51) CRBNPKMDUTALDH1A1LMNA
Thiourea SCHEMBL27613159 0.68 CRBN (0.44) CRBNPKMDUTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11092461-A None JP disclosed
EP-0896043-B1 Adhesive TOKUYAMA CORP (JP) 2002-10-23 EP disclosed
EP-0802194-B1 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORP (JP) 2002-06-19 EP disclosed
US-6133338-A TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF TOKUYAMA CORPORATION (JP) 2000-10-17 US disclosed
JP-H1192461-A DISULFIDE COMPOUND AND METAL SURFACE TREATING AGENT TOKUYAMA CORP 1999-04-06 JP disclosed
EP-0896043-A1 Adhesive TOKUYAMA CORPORATION (JP) 1999-02-10 EP disclosed
US-5795497-A Thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1998-08-18 US disclosed
EP-0802194-A2 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1997-10-22 EP disclosed