Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31383406 | 0.76 | IAPP (0.53) | — | |
| SCHEMBL27888690 | 0.74 | POLB (0.58) | PKML3MBTL1HTTPOLBTERT | |
| SCHEMBL31383411 | 0.73 | IAPP (0.55) | — | |
| SCHEMBL4250066 | 0.73 | TSHR (0.43) | PKMALDH1A1KDM4E | |
| SCHEMBL28467454 | 0.72 | IAPP (0.49) | — | |
| SCHEMBL22982305 | 0.72 | SELL (0.44) | ALDH1A1KDM4E | |
| SCHEMBL31618870 | 0.72 | SELL (0.44) | ALDH1A1KDM4E | |
| SCHEMBL24872489 | 0.69 | POLB (0.47) | PKML3MBTL1HTTPOLBTERT | |
| SCHEMBL29719025 | 0.66 | GABRA1 (0.56) | — | |
| SCHEMBL2475390 | 0.66 | GABRA1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092458-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | SAMARITAN PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | disclosed |