SCHEMBL5615232

SCHEMBL5615232

Cl[Zr](Cl)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.45
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
IDO1 P14902 1/20 0.41
TP53 P04637 1/20 0.41
TRPA1 O75762 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
F2 P00734 1/20 0.39
PLG P00747 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL19411334 0.84 TP53 (0.41) CALM1TSHRALDH1A1IDO1TP53
SCHEMBL5615183 0.82 CALM1 (0.45) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL727793 0.82 CALM1 (0.45) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL272369 0.75 CALM1 (0.50) CALM1TSHRALDH1A1LOXL2IDO1
Water SCHEMBL9141797 0.73 CALM1 (0.47) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL28833326 0.73 CALM1 (0.47) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL7593009 0.71 ALDH1A1 (0.46) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL7591882 0.71 TSHR (0.48) CALM1TSHRALDH1A1LOXL2IDO1
Hydrochloric Acid SCHEMBL6668783 0.71 CALM1 (0.45) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL7596414 0.71 ALDH1A1 (0.46) CALM1TSHRALDH1A1LOXL2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3436464-B1 METAL COMPLEXES UNIVATION TECH LLC (US) 2020-08-05 EP claimed
EP-3288953-B1 BIS(AMINOPHENYLPHENOL) LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM UNIVATION TECH LLC (US) 2021-01-06 EP disclosed
EP-2902400-B1 TRANSITION METAL COMPOUND, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2020-11-04 EP disclosed
EP-2902419-B1 METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2020-08-19 EP disclosed
CN-106866850-B Propylene polymer and molded article 三井化学株式会社 2020-07-03 CN disclosed
US-10696641-B2 Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom UNIVATION TECHNOLOGIES, LLC (US) 2020-06-30 US disclosed
US-10689314-B2 Methods for preparing bridged bi-aromatic ligands UNIVATION TECHNOLOGIES, LLC (US) 2020-06-23 US disclosed
US-10654029-B2 Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom UNIVATION TECHNOLOGIES, LLC (US) 2020-05-19 US disclosed
EP-3632920-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS Univation Technologies, LLC (US) 2020-04-08 EP disclosed
EP-3285923-B1 BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM UNIVATION TECH LLC (US) 2019-07-17 EP disclosed
EP-0570931-A2 Styrenic polymer, process for producing same and multi-layer material comprising same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed
EP-0546690-A1 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1993-06-16 EP disclosed
EP-0520811-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0520816-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696641-B2 Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom WASF2, WEE2, THEM6 CALM1 2922/4885TSHR 3246/4885ALDH1A1 2023/4885
US-10689314-B2 Methods for preparing bridged bi-aromatic ligands TYR, AOC2, BICRA CALM1 2470/4885TSHR 3980/4885ALDH1A1 1187/4885
US-10654029-B2 Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom WASF2, WEE2, PICALM CALM1 1935/4885TSHR 4569/4885ALDH1A1 1801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.