Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.60 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738587 | 0.85 | P2RX7 (0.71) | TAS1R3TAS1R1TAS1R2NPC1RAB9A | |
| SCHEMBL2078274 | 0.76 | LMNA (0.58) | TAS1R3TAS1R1TAS1R2NPC1RAB9A | |
| SCHEMBL702935 | 0.76 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2LMNAMEN1 | |
| SCHEMBL702936 | 0.76 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2LMNAMEN1 | |
| SCHEMBL1099137 | 0.75 | LMNA (0.57) | NPC1RAB9ALMNAGRM7MEN1 | |
| SCHEMBL2079156 | 0.75 | RAB9A (0.54) | NPC1RAB9ALMNACHRM4GRM7 | |
| SCHEMBL2079188 | 0.74 | NPC1 (0.56) | NPC1RAB9ALMNACHRM4GRM7 | |
| SCHEMBL4750983 | 0.74 | NPC1 (0.56) | NPC1RAB9ALMNAGRM7MEN1 | |
| SCHEMBL14988991 | 0.73 | NPC1 (0.52) | NPC1RAB9ALMNAP2RX7PRMT5 | |
| SCHEMBL10126900 | 0.73 | TAS1R3 (0.54) | TAS1R3TAS1R1TAS1R2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179839-B2 | Acylated indanyl amines and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
| US-20030055093-A1 | Acylated indanyl amines and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055093-A1 | Acylated indanyl amines and their use as pharmaceuticals | EDNRA, VEGFA, EDNRB | TAS1R3 2112/4885TAS1R1 1713/4885TAS1R2 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.