Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629432 | 0.96 | ALDH1A1 (0.35) | ABCG2CACNA2D1CACNB2CACNA1CPTGS1 | |
| SCHEMBL5632896 | 0.95 | GBA1 (0.31) | ABCG2PTGS1PPARGOPRK1 | |
| SCHEMBL5629600 | 0.81 | ABCG2 (0.37) | ABCG2CACNA2D1CACNB2CACNA1CPTGS1 | |
| SCHEMBL9468205 | 0.76 | SCN2A (0.42) | MEN1CYP3A4KMT2ACYP1A2CYP2C19 | |
| SCHEMBL11752241 | 0.75 | ALDH1A1 (0.37) | PTGS1PPARGMEN1CYP3A4KMT2A | |
| SCHEMBL217509 | 0.75 | EPHX2 (0.35) | EPHX2GMNNUSP2LMNACYP1A2 | |
| SCHEMBL8031341 | 0.75 | MMP2 (0.36) | EPHX2GMNNUSP2LMNACYP1A2 | |
| Sulfuric Acid SCHEMBL10539699 | 0.73 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL10337038 | 0.73 | FAAH (0.36) | PTGS1PPARGMEN1CYP3A4KMT2A | |
| SCHEMBL5630787 | 0.72 | NAAA (0.36) | GMNNUSP2LMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293406-A1 | POWER TRANSMISSION FLUID WITH ENHANCED FRICTION CHARACTERISTICS | AFTON CHEMICAL CORPORATION | 2007-12-20 | — | — | US | disclosed |