Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258234 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| SCHEMBL7920586 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL1137081 | 0.98 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| Pyrimidine SCHEMBL27956767 | 0.93 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| SCHEMBL827098 | 0.83 | MAPK1 (0.48) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| SCHEMBL8568179 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| Ethylene SCHEMBL27749127 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HTTLMNAMAPK1RAB9A | |
| SCHEMBL619318 | 0.76 | MAPT (0.52) | ALDH1A1HTTLMNAMAPK1MEN1 | |
| SCHEMBL6973083 | 0.76 | MAPT (0.56) | ALDH1A1HTTLMNAMAPK1MEN1 | |
| SCHEMBL10734254 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118721925-A | Electronic polycrystalline silicon multifunctional inner packaging material and preparation method thereof | 四川固朔新材料有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-117586250-A | Preparation method of human respiratory syncytial virus inhibitor intermediate | 潍坊汇韬化工有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-115322190-B | Pyridoimidazole acyl sulfonamide derivative, and preparation method and application thereof | 山东大学 | 2023-09-22 | — | — | CN | claimed |
| WO-2023143034-A1 | PYRIDOIMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2023-08-03 | — | — | WO | claimed |
| CN-116351100-A | System and method for extracting nitro reaction product by supercritical carbon dioxide | 天津凯莱英医药科技发展有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-115322190-A | Pyridoimidazole acylsulfonamide derivative and preparation method and application thereof | 山东大学 | 2022-11-11 | — | — | CN | claimed |
| CN-113956268-B | 6-bromo-1-chlorobenzothiophene [2,3-c ] pyridine and synthetic method | 西安欧得光电材料有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114478522-A | Pyridoimidazole derivative and preparation method and application thereof | 山东大学 | 2022-05-13 | — | — | CN | claimed |
| CN-113956268-A | 6-bromo-1-chlorobenzothiophene [2,3-c ] pyridine and synthetic method | 西安欧得光电材料有限公司 | 2022-01-21 | — | — | CN | claimed |
| CN-112707860-A | Synthesis method of active intermediate 4-chloro-3-nitropyridine | 南京波普生物医药研发有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-100439367-C | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | AVENTIS PHARMA INC (US) | 2008-12-03 | — | — | CN | claimed |
| US-20080200496-A1 | SUBSTITUTED 1H-PYRROLO[3,2-b, 3,2-c, and 2,3-c]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Ie | AVENTIS PHARMACEUTICALS INC. (US) | 2008-08-21 | — | — | US | claimed |
| CN-101245066-A | Method for producing 7-alkoxyl-2, 9-diazafluorene | UNIV FUDAN (CN) | 2008-08-20 | — | — | CN | claimed |
| US-7348326-B2 | Heteroaryl fused aminoalkyl imidazole derivatives: selective modulators of GABAa receptors | NEUROGEN CORPORATION (US) | 2008-03-25 | — | — | US | claimed |
| EP-1747220-A1 | SUBSTITUTED 1H-PYRROLO 3,2-B, 3,2-C, AND 2,3-C¨PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | Aventis Pharmaceuticals Inc. (US) | 2007-01-31 | — | — | EP | claimed |
| CN-1906194-A | Substituted 1H-pyrrolo [3, 2-b, 3, 2-c and 2, 3-c ] pyridine-2-carboxamides and related analogs as inhibitors of casein kinase ie | AVENTIS PHARMA INC (US) | 2007-01-31 | — | — | CN | claimed |
| WO-2005061498-A1 | SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMACEUTICALS INC. (US) | 2005-07-07 | — | — | WO | claimed |
| US-20050131012-A1 | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | AVENTIS PHARMACEUTICALS INC. (US) | 2005-06-16 | — | — | US | claimed |
| EP-0088023-B1 | PYRIDO(3',4':4,5)FURO(3,2-G) COUMARINES OR PYRIDO(3,4-H)PSORALENES, PREPARATION, USE IN COSMETOLOGY AND AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1987-01-14 | — | — | EP | claimed |
| US-4266060-A | ANTITUMOR ANTIVIRAL AGENTS FOR TREATMENT OF CANCER | AGENCE NATIONALE DE VAL ORISATION DE LA RECHERCHE (ANVAR) (FR) | 1981-05-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200496-A1 | SUBSTITUTED 1H-PYRROLO[3,2-b, 3,2-c, and 2,3-c]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Ie | CSNK1E, CSNK1G3, CSNK2A3 | ALDH1A1 3613/4885HTT 3995/4885LMNA 589/4885 |
| US-20050131012-A1 | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | CSNK2A3, PACSIN2, CSNK1G3 | ALDH1A1 4044/4885HTT 3317/4885LMNA 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.