Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563519 | 0.81 | AKR1C3 (0.52) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 | |
| SCHEMBL5496166 | 0.80 | TP53 (0.33) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| SCHEMBL3672023 | 0.79 | AKR1C3 (0.50) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 | |
| SCHEMBL3226792 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 | |
| SCHEMBL689448 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 | |
| SCHEMBL22634102 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 | |
| SCHEMBL563363 | 0.79 | AKR1C3 (0.46) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 | |
| SCHEMBL5488504 | 0.78 | CA2 (0.39) | CYP2C9CYP3A4TP53MEN1KMT2A | |
| SCHEMBL16266991 | 0.78 | THRB (0.49) | AKR1C3CYP3A4ALDH1A1TSHRMAPT | |
| SCHEMBL27808245 | 0.78 | AKR1C3 (0.48) | AKR1C3AKR1C1CYP2C9CYP3A4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609318-B2 | Radiation-sensitive resin composition, method for forming resist pattern and polymer | JSR CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20120034560-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND POLYMER | JSR CORPORATION (JP) | 2012-02-09 | — | — | US | disclosed |