Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.32 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563697 | 0.78 | AKR1C3 (0.50) | CYP1A2MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL5496166 | 0.75 | TP53 (0.33) | JUNCYP1A2CYP2C19TP53CYP3A4 | |
| SCHEMBL16266991 | 0.73 | THRB (0.49) | CA2CYP1A2CYP3A4 | |
| SCHEMBL2171752 | 0.66 | CA2 (0.71) | CA2CA4CA5ATDP1CYP1A2 | |
| SCHEMBL5572931 | 0.65 | CA2 (0.50) | CA2CA4CA5ATDP1 | |
| SCHEMBL31307462 | 0.65 | CA2 (0.40) | CA2CA4CA5ATDP1CYP1A2 | |
| SCHEMBL812027 | 0.64 | ALDH1A1 (0.52) | CA2CA4CA5ATDP1CYP1A2 | |
| SCHEMBL13883761 | 0.63 | F3 (0.57) | CA2CA4CA5AJUNCYP1A2 | |
| SCHEMBL4905770 | 0.63 | TRPA1 (0.47) | CYP1A2CYP2C19MEN1KMT2ACYP3A4 | |
| SCHEMBL4905778 | 0.63 | TRPA1 (0.47) | CYP1A2CYP2C19MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010428-A1 | Inhibitors of signal transduction and activator of transcription 3 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2007-01-11 | — | — | US | disclosed |