Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 15/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 13/20 | 0.58 |
| ▸ | TUBB | P07437 | 13/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 13/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 13/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 13/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 13/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 13/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031028 | 0.80 | TUBB1 (0.78) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5027099 | 0.74 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5026223 | 0.73 | TUBB1 (0.87) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5026295 | 0.72 | TUBB1 (0.72) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27686995 | 0.71 | DYRK1A (0.55) | MTNR1AMTNR1BKDM4EALDH1A1RXFP1 | |
| SCHEMBL3916211 | 0.70 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5638213 | 0.70 | KDM4E (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29533596 | 0.69 | KDM4E (0.68) | KDM4EALDH1A1RXFP1 | |
| SCHEMBL2330779 | 0.69 | KDM4E (0.68) | KDM4EALDH1A1RXFP1 | |
| SCHEMBL5027066 | 0.69 | TUBB1 (0.76) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082872-A1 | Indole-containing compounds with anti-tubulin and vascular targeting activity | BAYLOR UNIVERSITY | 2007-04-12 | — | — | US | disclosed |
| WO-2004099139-A1 | INDOLE-CONTAINING COMPOUNDS WITH ANTI-TUBULIN AND VASCULAR TARGETING ACTIVITY | BAYLOR UNIVERSITY (US) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082872-A1 | Indole-containing compounds with anti-tubulin and vascular targeting activity | TUBB3, TUBB1, TUBB | TUBB1 2/4885TUBB4A 5/4885TUBB 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.