SCHEMBL563713

SCHEMBL563713

O=C(O)C(=CF)C(C1CCCCCCCCC1)(C1CCCCCCCCC1)C1CCCCCCCCC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704502 0.82 HTT (0.33) KEAP1NFE2L2CES2CES1
SCHEMBL7988774 0.82 KEAP1 (0.32) KEAP1NFE2L2CES2CES1
SCHEMBL1533116 0.78 GRIK1 (0.40) KEAP1NFE2L2
SCHEMBL1263148 0.78 GRIK1 (0.40) KEAP1NFE2L2
SCHEMBL15410424 0.76 GRIK1 (0.39) KEAP1NFE2L2
SCHEMBL7988737 0.72 MEN1 (0.33)
SCHEMBL8395889 0.72 CES2 (0.36) KEAP1NFE2L2CES2CES1
SCHEMBL873007 0.71 KEAP1 (0.42) KEAP1NFE2L2CES2CES1
SCHEMBL2846765 0.71 KEAP1 (0.42) KEAP1NFE2L2CES2CES1
Bicarbonate SCHEMBL7556709 0.69 CES2 (0.38) KEAP1NFE2L2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9465291-B2 Radiation-sensitive resin composition, polymer, compound, and method for producing compound JSR CORPORATION (JP) 2016-10-11 US disclosed
US-20140186771-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, COMPOUND, AND METHOD FOR PRODUCING COMPOUND JSR CORPORATION (JP) 2014-07-03 US disclosed
US-8609318-B2 Radiation-sensitive resin composition, method for forming resist pattern and polymer JSR CORPORATION (JP) 2013-12-17 US disclosed
US-20120034560-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND POLYMER JSR CORPORATION (JP) 2012-02-09 US disclosed