Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CPT1A | P50416 | 7/20 | 0.48 |
| ▸ | CPT2 | P23786 | 5/20 | 0.48 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229273 | 0.85 | GAA (0.56) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5637475 | 0.81 | KDM4E (0.51) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5640744 | 0.80 | KDM4E (0.49) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5640756 | 0.80 | KDM4E (0.49) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL14515747 | 0.76 | KDM4E (0.45) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5638260 | 0.75 | ALDH1A1 (0.69) | KDM4EGAAALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL5638116 | 0.75 | SMN1; SMN2 (0.50) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11424895 | 0.72 | CPT1A (0.67) | ALDH1A1SMN1; SMN2CPT1ACPT2CPT1B | |
| SCHEMBL5640394 | 0.72 | KDM4E (0.56) | KDM4EMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4968957 | 0.72 | DPP4 (0.49) | KDM4EGAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220856-B2 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-20040072818-A1 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072818-A1 | Substituted quinoline CCR5 receptor antagonists | CCR5, CXCR3, CCR2 | KDM4E 3993/4885GAA 4333/4885MEN1 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.