SCHEMBL564293

SCHEMBL564293

C=CCNc1c(O)cccc1Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
GLA P06280 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TTR P02766 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 1/20 0.38
HIF1A Q16665 1/20 0.38
TGM2 P21980 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.36
DPP4 P27487 1/20 0.36
KDM4E B2RXH2 2/20 0.35
CAMK2A Q9UQM7 1/20 0.35
PNLIP P16233 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566068 0.81 KMT2A (0.39) GAAHTTRAB9AKMT2AMEN1
SCHEMBL564910 0.79 TSHR (0.43) GAAGLAHTTRAB9ASMN1; SMN2
SCHEMBL9772754 0.76 TSHR (0.53) GAAGLAHTTRAB9ASMN1; SMN2
SCHEMBL9836585 0.75 L3MBTL1 (0.46) GAAHTTKMT2AMAPTHIF1A
SCHEMBL11667005 0.75 TTR (0.42) GAAHTTTTRKMT2AALDH1A1
SCHEMBL565762 0.74 ALDH1A1 (0.40) GAAGLAHTTRAB9ASMN1; SMN2
SCHEMBL15354791 0.71 RAB9A (0.44) GAAGLAHTTRAB9ASMN1; SMN2
SCHEMBL566190 0.71 GAA (0.48) GAAGLAHTTRAB9ASMN1; SMN2
SCHEMBL565603 0.71 GAA (0.48) GAAGLAHTTRAB9ASMN1; SMN2
SCHEMBL10338492 0.70 GAA (0.43) GAAGLAHTTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 GAA 3993/4885GLA 4099/4885HTT 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.