Sugi Predict

Sugi Predict / Compounds / SCHEMBL566068

SCHEMBL566068

SCHEMBL566068

C=CCNc1c(O)cccc1-c1cccc(Oc2cccc(-c3cccc(O)c3NCC=C)c2NCC=C)c1NCC=C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.39
▸ MAPT P10636 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ ADRB2 P07550 1/20 0.35
▸ ADRB1 P08588 1/20 0.35
▸ HTT P42858 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ LMNA P02545 2/20 0.34
▸ MITF O75030 1/20 0.34
▸ NSD2 O96028 1/20 0.34
▸ CASP3 P42574 1/20 0.34
▸ SENP8 Q96LD8 1/20 0.34
▸ SENP7 Q9BQF6 1/20 0.34
▸ SENP6 Q9GZR1 1/20 0.34
▸ HPGD P15428 2/20 0.33
▸ GABRA1 P14867 1/20 0.33
▸ GABRB2 P47870 1/20 0.33
▸ RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565762 0.89 ALDH1A1 (0.40) KMT2AMAPTMEN1HIF1AHTT
Ether SCHEMBL566067 0.82 MAPT (0.39) KMT2AMAPTMEN1HIF1AHTT
SCHEMBL564293 0.81 GAA (0.42) KMT2AMAPTMEN1HIF1AHTT
SCHEMBL565941 0.69 ALDH1A1 (0.36) KMT2AMAPTMEN1HIF1AHTT
SCHEMBL31744538 0.68 KMT2A (0.45) KMT2AMAPTMEN1HIF1AALDH1A1
SCHEMBL31744578 0.67 LIG1 (0.45) KMT2AMAPTMEN1ADRB2ADRB1
SCHEMBL7781174 0.66 GABRA1 (0.41) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL2363598 0.65 CA2 (0.41) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL564626 0.65 GABRA1 (0.48) KMT2AMAPTMEN1HIF1AHTT
SCHEMBL2859431 0.65 MAPT (0.51) KMT2AMAPTMEN1HTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 KMT2A 2278/4885MAPT 3886/4885MEN1 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.