SCHEMBL1532408

SCHEMBL1532408

O=C(O)CC(=O)CCc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.79
KEAP1 Q14145 1/20 0.68
FFAR1 O14842 3/20 0.63
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
HDAC1 Q13547 3/20 0.57
ALDH1A1 P00352 2/20 0.57
HDAC3 O15379 1/20 0.57
MAPK1 P28482 1/20 0.57
ADRA1A P35348 1/20 0.57
HDAC4 P56524 1/20 0.57
SLC6A3 Q01959 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57
HDAC9 Q9UKV0 1/20 0.57
HDAC5 Q9UQL6 1/20 0.57
MAPT P10636 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598977 0.91 KEAP1 (0.67) MMP12KEAP1FFAR1HDAC2HDAC8
SCHEMBL27474155 0.89 KEAP1 (0.64) MMP12KEAP1FFAR1HDAC2HDAC8
SCHEMBL7239123 0.88 HDAC1 (0.70) MMP12KEAP1FFAR1HDAC2HDAC8
SCHEMBL497371 0.86 KEAP1 (0.73) MMP12KEAP1FFAR1HDAC2HDAC8
SCHEMBL11295192 0.84 MAPT (0.72) MMP12KEAP1HDAC2HDAC8HDAC6
SCHEMBL107423 0.84 KEAP1 (0.70) MMP12KEAP1FFAR1HDAC2HDAC8
SCHEMBL712597 0.84 KEAP1 (0.70) MMP12KEAP1FFAR1HDAC2HDAC8
SCHEMBL27550070 0.84 FFAR1 (0.75) MMP12FFAR1HDAC1TDP1FFAR4
SCHEMBL2871406 0.83 FFAR1 (0.77) MMP12FFAR1TDP1FFAR4
SCHEMBL2862583 0.83 MMP12 (0.68) MMP12KEAP1FFAR1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-115011576-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-10-25 CN claimed
CN-114990084-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-08-23 CN claimed
CN-115161300-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-08-23 CN claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
CN-115161300-A Aquilaria sinensis-derived III-type polyketide synthase AsPKS3 and coding gene and application thereof 中国医学科学院药用植物研究所 2022-10-11 CN claimed
CN-115011576-A Aquilaria sinensis-derived III-type polyketide synthase AsPKS5, and coding gene and application thereof 中国医学科学院药用植物研究所 2022-09-06 CN claimed
CN-114990084-A Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and coding gene and application thereof 中国医学科学院药用植物研究所 2022-09-02 CN claimed
EP-2829524-A1 Resin mixture, reaction resin mortar, multi-component mortar system and their use HILTI Aktiengesellschaft (LI) 2015-01-28 EP claimed
EP-2829525-A1 Reaction resin mortar, multi-component mortar system and their use HILTI Aktiengesellschaft (LI) 2015-01-28 EP claimed
WO-2011151701-A1 6 - METHYL - 4 - PHENYL - 5 - ( PHENYL OR CYCLOALKYL) CARBAMOYL - 1,2,3, 4 - TETRAHYDROPYRIMIDIN- 2 - ONE DERIVATIVES AS ANTITUBERCULAR AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-08 WO claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
US-20030198718-A1 Process for improving the durability of, and/or stabilizing, microbially perishable products SCHUR JORG PETER (DE) 2003-10-23 US claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
EP-0912467-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1999-05-06 EP claimed
WO-1998000375-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1998-01-08 WO claimed
US-5441766-A Employing as precursor copper beta-ketoester alone or with Lewis base ligand in presence or absence of hydrogen KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1995-08-15 US claimed