Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EYA2 | O00167 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364023 | 0.89 | TRPM5 (0.44) | ALDH1A1MAPTHPGDPTGER1MAPK1 | |
| SCHEMBL3367784 | 0.80 | SMN1; SMN2 (0.37) | MAPTMAPK1CA12CA1CA2 | |
| SCHEMBL3367790 | 0.76 | HDAC1 (0.41) | LMNAAKR1C2HTTSMN1; SMN2KMT2A | |
| SCHEMBL1856515 | 0.72 | MAPT (0.44) | ALDH1A1MAPTPTGER1MAPK1LMNA | |
| SCHEMBL5643236 | 0.71 | MAPT (0.62) | ALDH1A1MAPTHPGDPTGER1LMNA | |
| SCHEMBL5643240 | 0.71 | MAPT (0.62) | ALDH1A1MAPTHPGDPTGER1LMNA | |
| SCHEMBL3366543 | 0.69 | TP53 (0.48) | ALDH1A1MAPTPTGER1SMN1; SMN2MEN1 | |
| SCHEMBL3366546 | 0.67 | TP53 (0.49) | ALDH1A1MAPTPTGER1SMN1; SMN2MEN1 | |
| SCHEMBL1858551 | 0.66 | MAPT (0.41) | ALDH1A1MAPTPTGER1MAPK1LMNA | |
| SCHEMBL31612237 | 0.65 | AKR1C2 (0.75) | ALDH1A1MAPTAKR1C2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |