Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059081 | 0.91 | MAPT (0.55) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL5086187 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL2491603 | 0.84 | CA12 (0.61) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL6718454 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL9141441 | 0.82 | MAPT (0.54) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL7079697 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL1966571 | 0.82 | MAPT (0.54) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL5626568 | 0.82 | LMNA (0.62) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL316956 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNATSHRMEN1 | |
| SCHEMBL13909369 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891461-B | Synthesis method of SERD intermediate | 罗欣药业(上海)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-116891461-A | Synthesis method of SERD intermediate | 罗欣药业(上海)有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-108484500-A | A kind of preparation method of 1- trifluoroethyls isoquinolin | 四川理工学院 | 2018-09-04 | — | — | CN | disclosed |
| CN-107400096-A | A kind of synthetic method of triazole compounds | 湖南华腾制药有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-106543081-A | A kind of preparation method of 1 fluoroalkyl isoquinolin | 四川理工学院 | 2017-03-29 | — | — | CN | disclosed |
| US-7226951-B2 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| US-20050176689-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN, INC. | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176689-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | CYP1A2, CYP2A7, CYP3A7 | ALDH1A1 96/4885MAPT 4562/4885CA1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.