SCHEMBL564403

SCHEMBL564403

Cc1ccc(S(=O)(=O)OCCOCCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
CA1 P00915 3/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
STAT3 P40763 2/20 0.43
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 2/20 0.39
CYP2D6 P10635 1/20 0.38
PPARG P37231 1/20 0.38
PSMD10 O75832 1/20 0.38
CA2 P00918 2/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
MMP1 P03956 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30244568 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL16898428 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL15416739 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL483840 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL1742594 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL916053 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL23417950 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL7519771 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL11516145 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3
SCHEMBL16899885 1.00 ALDH1A1 (0.46) ALDH1A1CA1CA12CA9STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678665-A1 A POLYMER, PREPARATION METHOD THEREOF, POROUS MEMBRANE CONTAINING THE POLYMER AND APPLICATION OF THE MEMBRANE Syai UK Ltd (GB) 2026-01-14 EP claimed
CN-118684823-A Polymer, preparation method thereof, porous membrane containing polymer and application of membrane 欧态科技(无锡)有限公司 2024-09-24 CN claimed
CN-117772154-A Packing for glycosylated hemoglobin chromatographic column and preparation method thereof 无锡博慧斯生物医药科技有限公司 2024-03-29 CN claimed
CN-117049967-A Preparation method and active application of 2, 6-dinitro-3, 4-dimethylphenol derivative 西华大学 2023-11-14 CN claimed
US-20230303792-A1 Additive for Reducing Polyurethane Foam Degradation HUNTSMAN INTERNATIONAL LLC 2023-09-28 US claimed
EP-4196514-A1 ADDITIVE FOR REDUCING POLYURETHANE FOAM DEGRADATION Huntsman International LLC (US) 2023-06-21 EP claimed
US-20230078913-A1 ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS PROTEOLYSIS TARGETING CHIMERA LIGANDS ESSA PHARMA INC. (CA) 2023-03-16 US claimed
CN-114269331-A Androgen receptor modulators and methods of use as proteolytic targeting chimeric ligands 埃萨制药股份有限公司 2022-04-01 CN claimed
WO-2022034151-A1 ADDITIVE FOR REDUCING POLYURETHANE FOAM DEGRADATION HUNTSMAN INTERNATIONAL LLC (US) 2022-02-17 WO claimed
EP-3946292-A1 ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS PROTEOLYSIS TARGETING CHIMERA LIGANDS Essa Pharma, Inc. (CA) 2022-02-09 EP claimed
WO-2020198711-A1 ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS PROTEOLYSIS TARGETING CHIMERA LIGANDS ESSA PHARMA, INC. (CA) 2020-10-01 WO claimed
EP-3658548-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR Arvinas Operations, Inc. (US) 2020-06-03 EP claimed
CN-111205472-A Preparation method of solid fluorescent dye based on multiple hydrogen bonds 常州大学 2020-05-29 CN claimed
WO-2019023553-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR Arvinas, Inc. (US) 2019-01-31 WO claimed
US-20170327469-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR ARVINAS OPERATIONS, INC. 2017-11-16 US claimed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
US-20260055097-A9 NRF2 PROTEIN DEGRADERS GANYMEDE ONCOLOGY INC (US) 2026-02-26 US disclosed
WO-1999061912-A1 MOLECULAR ROD AND USES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1999-12-02 WO disclosed
EP-0824537-A1 IODINE DERIVATIVES OF MONOSACCHARIDES USEFUL AS RADIOPHARMACEUTICAL PRODUCTS CIS BIO INTERNATIONAL (FR) 1998-02-25 EP disclosed
WO-1996034872-A1 IODINE DERIVATIVES OF MONOSACCHARIDES USEFUL AS RADIOPHARMACEUTICAL PRODUCTS CIS BIO INTERNATIONAL (FR) 1996-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230078913-A1 ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS PROTEOLYSIS TARGETING CHIMERA LIGANDS AR, PSMA1, SHBG ALDH1A1 3367/4885CA1 3020/4885CA12 2897/4885
US-20170327469-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR AR, MDM2, ESRRA ALDH1A1 514/4885CA1 2519/4885CA12 2708/4885
US-20260055097-A9 NRF2 PROTEIN DEGRADERS KEAP1, NFE2L2, NFE2 ALDH1A1 1094/4885CA1 3789/4885CA12 3947/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 ALDH1A1 2777/4885CA1 3147/4885CA12 3515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.