Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21277861 | 0.86 | PSIP1 (0.61) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3880988 | 0.82 | PSIP1 (0.47) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1941301 | 0.78 | PSIP1 (0.47) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28906881 | 0.78 | CA2 (0.53) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3882769 | 0.78 | PSIP1 (0.74) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3060869 | 0.78 | PSIP1 (0.47) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2054720 | 0.78 | ALDH1A1 (0.44) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10619867 | 0.78 | ALDH1A1 (0.47) | PSIP1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5325324 | 0.76 | CA2 (0.56) | PSIP1ALDH1A1CA2SMN1; SMN2KMT2A | |
| SCHEMBL1428902 | 0.75 | ENPP2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | PSIP1 2510/4885ALDH1A1 1438/4885CYP3A4 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.