Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721853 | 0.84 | POLB (0.72) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL28734394 | 0.84 | POLB (0.72) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL13166882 | 0.79 | POLB (0.76) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL5144511 | 0.78 | POLB (0.86) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL7257110 | 0.77 | MEN1 (0.72) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL7719057 | 0.77 | POLB (0.71) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL30612630 | 0.76 | POLB (0.75) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL247350 | 0.76 | POLB (0.75) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL7718043 | 0.75 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL3046406 | 0.75 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138546-B2 | N-(2-chlorophenyl) hydroxy- or alkoxyalkanamides, e.g.,N-(5-Chloro-2-hydroxyphenyl)-2-(2-hydroxyphenoxy)acetamid e); can deliver a broad range of active agents by various routes. | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-20030216287-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-11-20 | — | — | US | disclosed |
| EP-1317412-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002016309-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216287-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | POLB 985/4885MEN1 1531/4885KMT2A 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.