SCHEMBL5648029

SCHEMBL5648029

N#CSC(Cc1ccccc1)S(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 5/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MMP2 P08253 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
MEN1 O00255 1/20 0.40
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
PTPRF P10586 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPN11 Q06124 1/20 0.40
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3414663 0.72 HSD11B1 (0.47) KMT2AHTTALDH1A1NPC1RAB9A
SCHEMBL3760717 0.71 LOXL2 (0.43) KMT2AALDH1A1CYP1A2CYP2C19MEN1
SCHEMBL6544697 0.70 ALDH1A1 (0.58) KMT2AHTTALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL28043285 0.70 ESR2 (0.49) KMT2AHTTALDH1A1NPC1RAB9A
SCHEMBL10566442 0.67 ESR2 (0.49) KMT2AHTTALDH1A1NPC1RAB9A
SCHEMBL9629229 0.67 KMT2A (0.46) KMT2AHTTALDH1A1RAB9ASMN1; SMN2
SCHEMBL15994105 0.67 EPHX1 (0.61) KMT2AALDH1A1NPC1RAB9ATP53
SCHEMBL20380076 0.67 HTT (0.64) KMT2AHTTALDH1A1NPC1RAB9A
SCHEMBL29274272 0.67 CYP1A2 (0.53) KMT2AHTTALDH1A1NPC1RAB9A
SCHEMBL6543954 0.66 CA2 (0.61) KMT2AALDH1A1MMP2CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8242062-B2 IMS detection of chemical markers in petroleum products AUTHENTIX, INC. (US) 2012-08-14 US disclosed
US-20070212785-A1 IMS DETECTION OF CHEMICAL MARKERS IN PETROLEUM PRODUCTS AUTHENTIX, INC. (US) 2007-09-13 US disclosed