Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 4/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650519 | 0.83 | LMNA (0.44) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27690017 | 0.82 | CCR2 (0.38) | CCR2L3MBTL1 | |
| SCHEMBL5652344 | 0.81 | NMT1 (0.41) | ALDH1A1LMNANMT1 | |
| SCHEMBL19859300 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNACCR2KIF11L3MBTL1 | |
| SCHEMBL5647150 | 0.79 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL568535 | 0.76 | ADH1B (0.39) | ALDH1A1LMNACCR2CXCR4 | |
| SCHEMBL2371748 | 0.75 | NMT1 (0.56) | ALDH1A1LMNACCR2NMT1KAT6A | |
| SCHEMBL2371266 | 0.74 | CCR2 (0.53) | ALDH1A1LMNACCR2KAT6A | |
| SCHEMBL17342883 | 0.73 | GAA (0.48) | ALDH1A1LMNACCR2NMT1KAT6A | |
| SCHEMBL5648958 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| CN-1863793-A | Cyclic tertiary amine compound | SANKYO CO (JP) | 2006-11-15 | — | — | CN | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049620-A1 | Cyclic tertiary amine compound | MYD88, IL5, BRD4 | ALDH1A1 1438/4885LMNA 4146/4885CCR2 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.