Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647796 | 0.82 | TRPA1 (0.43) | SLC5A2EPHX1NPC1CYP1A2CYP2C19 | |
| SCHEMBL7362430 | 0.79 | TAAR1 (0.40) | — | |
| SCHEMBL7277764 | 0.78 | MIF (0.53) | CPA3NPC1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3906596 | 0.76 | SLC5A2 (0.52) | SLC5A2EPHX1NPC1CYP1A2CYP2C19 | |
| SCHEMBL30846601 | 0.74 | EPHX1 (0.48) | ANPEPEPHX1CYP1A2 | |
| SCHEMBL30846613 | 0.74 | EPHX1 (0.48) | ANPEPEPHX1CYP1A2 | |
| SCHEMBL3289195 | 0.74 | EPHX1 (0.48) | ANPEPEPHX1CYP1A2 | |
| SCHEMBL6570901 | 0.74 | ALDH1A1 (0.40) | SLC5A2EPHX1NPC1ALDH1A1MAPT | |
| SCHEMBL131911 | 0.73 | ALOX5 (0.37) | NPC1ALDH1A1MAPTCES2CES1 | |
| Hydrochloric Acid SCHEMBL9482622 | 0.73 | EPHX1 (0.47) | ANPEPEPHX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288560-B2 | Spirocyclic cyclohexane derivatives | GRUENENTHAL GMBH (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20050187281-A1 | Spirocyclic cyclohexane derivatives | GRUENENTHAL GMBH (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187281-A1 | Spirocyclic cyclohexane derivatives | PKD2, PKD1, VKORC1 | ANPEP 2982/4885CPA3 3041/4885FOLH1 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.