Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPA3 | P15088 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177437 | 0.89 | MIF (0.42) | MIFCPA1CPB1CPA3CPB2 | |
| SCHEMBL658090 | 0.86 | CES2 (0.46) | ALDH1A1MAPTTSHRCES2CES1 | |
| SCHEMBL27477104 | 0.85 | MME (0.50) | LTA4H | |
| SCHEMBL6176632 | 0.84 | PKM (0.55) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8309560 | 0.84 | TSHR (0.44) | ALDH1A1MAPTTSHRCYP2C19NPC1 | |
| SCHEMBL5647796 | 0.81 | TRPA1 (0.43) | ALDH1A1MAPTTSHRCES2CES1 | |
| SCHEMBL22775864 | 0.80 | CES2 (0.41) | ALDH1A1MAPTTSHRCES2CES1 | |
| SCHEMBL341042 | 0.80 | GABBR2 (0.56) | TSHRCES2CES1KEAP1CYP1A2 | |
| SCHEMBL27878861 | 0.80 | ALOX5 (0.41) | ALDH1A1MAPTTSHRCES2CES1 | |
| SCHEMBL5651198 | 0.78 | ANPEP (0.44) | CPA3ALDH1A1MAPTTSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177821-C | Matrix metalloprotease inhibitors | - | 2004-12-01 | — | — | CN | disclosed |
| CN-1160045-A | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 1997-09-24 | — | — | CN | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |