Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307932 | 0.83 | ALDH1A1 (0.39) | TYRSCN10AALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL1527058 | 0.80 | ALDH1A1 (0.57) | TYRTRIM24TRIM33ALDH1A1HPGD | |
| SCHEMBL5643460 | 0.79 | TYR (0.50) | TYRTRIM24TRIM33ALDH1A1HPGD | |
| SCHEMBL1743976 | 0.78 | ALDH1A1 (0.59) | SCN10AALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL29406501 | 0.75 | ALDH1A1 (0.42) | SCN10AALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL5643937 | 0.75 | TYR (0.46) | TYRTRIM24TRIM33ALDH1A1HPGD | |
| SCHEMBL6105846 | 0.75 | CNR1 (0.51) | TYRTRIM24TRIM33ALDH1A1HPGD | |
| SCHEMBL7587116 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDHSD17B10TDP1PRKDC | |
| SCHEMBL537374 | 0.73 | POLB (0.56) | TYRTRIM24TRIM33PIK3CDPIK3CA | |
| SCHEMBL5645422 | 0.72 | CNR1 (0.47) | TYRTRIM24TRIM33ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259266-B2 | Benzopyran compounds useful for treating inflammatory conditions | PHARMACIA CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | PTGES2, PTGER2, PTGS2 | TYR 488/4885TRIM24 3213/4885TRIM33 3760/4885 |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | PTGES2, PTGER2, PTGES | TYR 496/4885TRIM24 3411/4885TRIM33 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.