Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.59 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655807 | 0.76 | TAOK1 (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL31730308 | 0.76 | TAOK1 (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL22281511 | 0.75 | KMT2A (0.67) | SMN1; SMN2MAPTALDH1A1TSHRGAA | |
| SCHEMBL15613189 | 0.74 | ALDH1A1 (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL15613190 | 0.73 | KDM4E (0.58) | SMN1; SMN2ALDH1A1HPGDRXFP1GAA | |
| SCHEMBL4251761 | 0.73 | KDM4E (0.83) | SMN1; SMN2MAPTALDH1A1HPGDGAA | |
| SCHEMBL16872898 | 0.72 | ALDH1A1 (0.80) | SMN1; SMN2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL27202845 | 0.72 | ALDH1A1 (0.74) | SMN1; SMN2MAPTALDH1A1HPGDGAA | |
| SCHEMBL19665251 | 0.72 | MPO (0.67) | SMN1; SMN2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL2917327 | 0.71 | KMT2A (0.58) | SMN1; SMN2ALDH1A1HPGDTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | SMN1; SMN2 4552/4885MAPT 4207/4885ALDH1A1 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.