SCHEMBL31730308

SCHEMBL31730308

CCOCCCn1c(=S)[nH]c2cc(C(=O)NCC3COc4ccccc4O3)ccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TAOK1 Q7L7X3 1/20 1.00
▸ TAOK3 Q9H2K8 1/20 1.00
▸ MAPT P10636 3/20 0.66
▸ SMN1; SMN2 Q16637 3/20 0.66
▸ RXFP1 Q9HBX9 3/20 0.65
▸ ALDH1A1 P00352 5/20 0.64
▸ RECQL P46063 2/20 0.64
▸ TSHR P16473 2/20 0.64
▸ GAA P10253 1/20 0.61
▸ LMNA P02545 1/20 0.58
▸ HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5655807 1.00 TAOK1 (1.00) TAOK1TAOK3MAPTSMN1; SMN2RXFP1
SCHEMBL13091133 0.80 TAOK1 (0.67) TAOK1TAOK3MAPTSMN1; SMN2RXFP1
SCHEMBL5652363 0.76 SMN1; SMN2 (0.76) TAOK1TAOK3MAPTSMN1; SMN2RXFP1
SCHEMBL5652987 0.72 TAOK1 (0.56) TAOK1TAOK3MAPTSMN1; SMN2ALDH1A1
SCHEMBL13091006 0.68 SMN1; SMN2 (0.78) MAPTSMN1; SMN2RXFP1ALDH1A1RECQL
SCHEMBL16872917 0.66 SMN1; SMN2 (0.73) MAPTSMN1; SMN2RXFP1ALDH1A1RECQL
SCHEMBL15613301 0.66 SMN1; SMN2 (0.73) MAPTSMN1; SMN2RXFP1ALDH1A1RECQL
SCHEMBL16872898 0.65 ALDH1A1 (0.80) MAPTSMN1; SMN2RXFP1ALDH1A1RECQL
SCHEMBL19665251 0.65 MPO (0.67) MAPTSMN1; SMN2RXFP1ALDH1A1RECQL
SCHEMBL5650906 0.65 RAB9A (0.61) TAOK1MAPTSMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354151-A1 INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE KYOTO PREFECTURAL PUBLIC UNIV CORP (JP) 2025-11-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250354151-A1 INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE TNNI3, TNNC1, TNNT2 TAOK1 7/4885TAOK3 16/4885MAPT 4762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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