Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.56 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650906 | 0.82 | RAB9A (0.61) | TAOK1RAB9AHPGDSMN1; SMN2HTT | |
| SCHEMBL2952998 | 0.72 | HPGD (0.64) | RAB9AHPGDSMN1; SMN2HTTNPC1 | |
| SCHEMBL31730308 | 0.72 | TAOK1 (1.00) | TAOK1TAOK3HPGDSMN1; SMN2TSHR | |
| SCHEMBL5655807 | 0.72 | TAOK1 (1.00) | TAOK1TAOK3HPGDSMN1; SMN2TSHR | |
| SCHEMBL5653074 | 0.72 | RAB9A (0.60) | TAOK1RAB9AHPGDSMN1; SMN2HTT | |
| SCHEMBL5924184 | 0.68 | HPGD (0.61) | RAB9AHPGDSMN1; SMN2HTTNPC1 | |
| SCHEMBL29922125 | 0.68 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2HTTNPC1 | |
| SCHEMBL22861759 | 0.68 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2HTTNPC1 | |
| SCHEMBL26965086 | 0.68 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2HTTNPC1 | |
| SCHEMBL2159336 | 0.67 | HPGD (0.64) | HPGDSMN1; SMN2HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354151-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | KYOTO PREFECTURAL PUBLIC UNIV CORP (JP) | 2025-11-20 | — | — | US | disclosed |
| EP-4534091-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (JP) | 2025-04-09 | — | — | EP | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | EXELIXIS, INC. (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250354151-A1 | INHIBITORY AGENT FOR MYOCARDIAL CELL DEATH, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR MYOCARDIAL DISORDERS OR HEART FAILURE | TNNI3, TNNC1, TNNT2 | TAOK1 7/4885TAOK3 16/4885RAB9A 4119/4885 |
| US-20070208166-A1 | Tao Kinase Modulators And Method Of Use | TAOK1, TAOK3, MAP3K6 | TAOK1 1/4885TAOK3 2/4885RAB9A 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.