Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxycinnamic Acid SCHEMBL4657863 | 0.87 | TDP1 (0.55) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL27805505 | 0.87 | TDP1 (0.55) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL344148 | 0.87 | TDP1 (0.55) | THRBATMTDP1TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL4844856 | 0.81 | THRB (0.46) | THRBATMTDP1TAS1R3TAS1R1 | |
| SCHEMBL7773761 | 0.79 | ALOX5 (0.43) | THRBTDP1TAS1R3TAS1R1NPC1 | |
| 4-Methoxycinnamic Acid SCHEMBL910634 | 0.78 | TDP1 (0.62) | THRBATMTDP1TAS1R3TAS1R1 | |
| SCHEMBL29203311 | 0.77 | TDP1 (0.58) | THRBATMTDP1TAS1R3TAS1R1 | |
| Monoctanoin Component A SCHEMBL392377 | 0.77 | KDM4E (0.58) | THRBATMTDP1TAS1R3TAS1R1 | |
| Octinoxate SCHEMBL6036126 | 0.76 | TDP1 (0.76) | TDP1TAS1R3TAS1R1LMNAGSK3B | |
| 4-Methoxycinnamic Acid SCHEMBL16333598 | 0.75 | THRB (0.62) | THRBATMTDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105570-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2006-09-12 | — | — | US | disclosed |
| US-6703031-B1 | OXIDATIVE STRESS INHIBITOR; RETARDING AGING OF SKIN | AJINOMOTO CO., INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20030194417-A1 | Cysteine derivatives | AJINOMOTO CO. INC (JP) | 2003-10-16 | — | — | US | disclosed |
| US-6602492-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2003-08-05 | — | — | US | disclosed |
| US-20020115723-A1 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115723-A1 | Cysteine derivatives | NFE2L2, GCLC, KEAP1 | THRB 3075/4885ATM 1674/4885TDP1 2572/4885 |
| US-20030194417-A1 | Cysteine derivatives | NFE2L2, GCLC, KEAP1 | THRB 3075/4885ATM 1674/4885TDP1 2572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.