Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 7/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16964106 | 0.73 | POLB (0.44) | SMN1; SMN2TSHRHRH2HRH3POLB | |
| SCHEMBL5835647 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRHRH2DRD2HRH1 | |
| SCHEMBL21751210 | 0.71 | KMT2A (0.39) | HTTL3MBTL1ALDH1A1RECQLTDP1 | |
| SCHEMBL2666856 | 0.70 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRHRH2DRD2HRH1 | |
| SCHEMBL13851673 | 0.69 | HRH2 (0.52) | SMN1; SMN2TSHRHRH2DRD2HRH1 | |
| SCHEMBL5684644 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRHRH2DRD2HRH1 | |
| SCHEMBL18116109 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRHRH2DRD2HRH1 | |
| SCHEMBL1027537 | 0.69 | TRPM8 (0.49) | SMN1; SMN2POLBHTTL3MBTL1TDP1 | |
| SCHEMBL2569939 | 0.69 | APLNR (0.42) | HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL2001093 | 0.69 | HCRTR1 (0.39) | HTTL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105908-A1 | Thiazolimine compound and oxazolimine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105908-A1 | Thiazolimine compound and oxazolimine compound | CMA1, TH, NPR3 | SMN1; SMN2 3302/4885TSHR 724/4885HRH2 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.