Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657438 | 0.94 | HRH3 (0.56) | ALDH1A1SMN1; SMN2HTR4L3MBTL1LMNA | |
| SCHEMBL5655631 | 0.89 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2HTR4L3MBTL1KDM4E | |
| SCHEMBL5657766 | 0.86 | HRH3 (0.56) | SMN1; SMN2KDM4EHRH3HTR2AMEN1 | |
| SCHEMBL5654284 | 0.85 | KDM4E (0.60) | ALDH1A1SMN1; SMN2HTR4L3MBTL1KDM4E | |
| SCHEMBL5654228 | 0.84 | NPSR1 (0.55) | ALDH1A1SMN1; SMN2HTR4L3MBTL1TSHR | |
| SCHEMBL5656355 | 0.83 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EUSP2 | |
| SCHEMBL5656910 | 0.83 | HTR4 (0.58) | ALDH1A1SMN1; SMN2HTR4L3MBTL1KDM4E | |
| SCHEMBL14457584 | 0.81 | HTR4 (0.60) | ALDH1A1SMN1; SMN2HTR4L3MBTL1LMNA | |
| SCHEMBL5655862 | 0.81 | NPSR1 (0.59) | ALDH1A1HTR4L3MBTL1TSHRNPSR1 | |
| SCHEMBL5656389 | 0.81 | ADRA1D (0.65) | LMNAUSP2NPSR1DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20040058933-A1 | Aryl carbamate derivatives, preperation and use thereof | CEREP (FR) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058933-A1 | Aryl carbamate derivatives, preperation and use thereof | HTR4, HTR5A, HTR3C | ALDH1A1 1018/4885SMN1; SMN2 3970/4885HTR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.