Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230632 | 0.99 | GAA (0.41) | GAAFABP4FABP5DRD2DRD4 | |
| Bromide SCHEMBL7649880 | 0.97 | GAA (0.40) | GAAFABP4FABP5DRD2DRD4 | |
| Bromide SCHEMBL5034614 | 0.97 | GAA (0.40) | GAAFABP4FABP5DRD2DRD4 | |
| SCHEMBL14454734 | 0.97 | FABP4 (0.41) | GAAFABP4FABP5DRD2DRD4 | |
| Iodide SCHEMBL3454461 | 0.89 | DRD2 (0.42) | FABP4FABP5DRD2DRD4HDAC1 | |
| SCHEMBL29521317 | 0.88 | DRD2 (0.43) | FABP4FABP5DRD2DRD4HDAC1 | |
| SCHEMBL5133368 | 0.88 | DRD2 (0.43) | FABP4FABP5DRD2DRD4HDAC1 | |
| SCHEMBL21768355 | 0.87 | DRD2 (0.39) | GAADRD2DRD4HDAC1HDAC6 | |
| Bromide SCHEMBL28672149 | 0.87 | DRD2 (0.42) | FABP4FABP5DRD2DRD4HDAC1 | |
| Bromide SCHEMBL5833274 | 0.87 | DRD2 (0.42) | FABP4FABP5DRD2DRD4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802710-B1 | METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES | LUMINEX CORP (US) | 2016-02-24 | — | — | EP | disclosed |
| EP-2559738-B1 | Methods for forming dyed microspheres and populations of dyed microspheres | LUMINEX CORP (US) | 2014-07-09 | — | — | EP | disclosed |
| EP-2559738-A1 | Methods for forming dyed microspheres and populations of dyed microspheres | Luminex Corporation (US) | 2013-02-20 | — | — | EP | disclosed |
| US-8361169-B2 | Methods for forming dyed microspheres and populations of dyed microspheres | LUMINEX CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120035328-A1 | METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES | HOFFACKER KURT D (US) | 2012-02-09 | — | — | US | disclosed |
| US-8038734-B2 | Methods for forming dyed microspheres and populations of dyed microspheres | LUMINEX CORPORATION (US) | 2011-10-18 | — | — | US | disclosed |
| EP-1802710-A2 | METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES | Luminex Corporation (US) | 2007-07-04 | — | — | EP | disclosed |
| US-20060085925-A1 | Methods for forming dyed microspheres and populations of dyed microspheres | LUMINEX CORPORATION | 2006-04-27 | — | — | US | disclosed |
| WO-2006044413-A2 | METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES | LUMINEX CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035328-A1 | METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES | CD68, CD14, MYADM | GAA 712/4885FABP4 1241/4885FABP5 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.