Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.50 |
| ▸ | IAPP | P10997 | 4/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445878 | 0.88 | IAPP (0.55) | GABRA1GABRB2IAPPADAMTS4ALDH1A1 | |
| SCHEMBL29079403 | 0.86 | HSP90AA1 (0.52) | GABRA1GABRB2IAPPHSP90AA1ALDH1A1 | |
| SCHEMBL9049482 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2IAPPHMGB1ALOX5 | |
| SCHEMBL11785077 | 0.84 | ALDH1A1 (0.52) | GABRA1GABRB2IAPPALOX5PTGS2 | |
| SCHEMBL7393700 | 0.83 | ALOX5 (0.46) | GABRA1GABRB2IAPPHMGB1ALOX5 | |
| SCHEMBL5657934 | 0.80 | ALOX5 (0.65) | ALOX5PTGS2ALDH1A1LMNAHPGD | |
| SCHEMBL14114433 | 0.78 | HMGB1 (0.49) | GABRA1GABRB2IAPPHMGB1ALOX5 | |
| SCHEMBL10784130 | 0.78 | GABRA1 (0.55) | GABRA1GABRB2IAPPHMGB1HSP90AA1 | |
| SCHEMBL4574904 | 0.77 | TAAR1 (0.40) | ALDH1A1LMNAHSD17B10HSPA5TAAR1 | |
| SCHEMBL6944890 | 0.77 | TAAR1 (0.60) | CA2HSPA5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | claimed |
| CN-109929103-B | Method for preparing high-intrinsic-viscosity polyphenyl ether | 北京赛福瑞技术服务有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-116969816-A | Bisphenol compound and double-end hydroxyl low molecular weight polyphenyl ether | 北京赛福瑞技术服务有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116813900-A | Double-end hydroxyl low molecular weight polyphenyl ether and synthesis method thereof | 北京赛福瑞技术服务有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | disclosed |
| EP-0255230-B1 | PROCESS FOR PRODUCING POLYPHENYLENE ETHERS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-4895929-A | Process for producing polyphenylene ether, dispersing polyether in aqueous medium and heating dispersion | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0255230-A1 | Process for producing polyphenylene ethers | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| EP-0059958-B1 | PROCESS FOR PRODUCING POLYPHENYLENE OXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-06-04 | — | — | EP | disclosed |
| US-4588806-A | Polyphenylene ether resins having bimodal molecular weight distributions and method of their formation | GENERAL ELECTRIC COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4385168-A | FROM OXIDATIVE POLYMERIZATION OF PHENOLIC MONOMER IN PRESENCE OF MANGANIUM SALT AND HYDROXYAZO AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-24 | — | — | US | disclosed |
| EP-0059958-A1 | Process for producing polyphenylene oxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-09-15 | — | — | EP | disclosed |
| US-4098846-A | IMPACT STRENGTH | GENERAL ELECTRIC COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4054553-A | MANGANESE COMPLEX CATALYST | GENERAL ELECTRIC COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3972851-A | Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3965069-A | Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3962180-A | COPPER, MANGANESE OR COBALT AND AN AMINE CATALYST | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1976-06-08 | — | — | US | disclosed |
| US-3956242-A | Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |