Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 6/20 | 0.79 |
| ▸ | DRD2 | P14416 | 5/20 | 0.79 |
| ▸ | HTR2A | P28223 | 4/20 | 0.79 |
| ▸ | HTR7 | P34969 | 3/20 | 0.79 |
| ▸ | HTR2B | P41595 | 3/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.79 |
| ▸ | HTR5A | P47898 | 2/20 | 0.79 |
| ▸ | HTR6 | P50406 | 2/20 | 0.79 |
| ▸ | HTR2C | P28335 | 2/20 | 0.79 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.79 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.79 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.79 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.79 |
| ▸ | DRD4 | P21917 | 1/20 | 0.79 |
| ▸ | DRD5 | P21918 | 1/20 | 0.79 |
| ▸ | HRH2 | P25021 | 1/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.79 |
| ▸ | HTR1D | P28221 | 1/20 | 0.79 |
| ▸ | HTR1B | P28222 | 1/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367903 | 1.00 | DRD1 (0.79) | DRD1DRD2HTR2AHTR7HTR2B | |
| SCHEMBL31029794 | 1.00 | DRD1 (0.79) | DRD1DRD2HTR2AHTR7HTR2B | |
| Nantenine SCHEMBL1254591 | 0.88 | HTR2A (1.00) | DRD1DRD2HTR2AHTR7HTR2B | |
| Nantenine SCHEMBL1254592 | 0.88 | HTR2A (1.00) | DRD1DRD2HTR2AHTR7HTR2B | |
| Boldine SCHEMBL29973042 | 0.85 | ALDH1A1 (1.00) | DRD1DRD2HTR2AHTR7HTR2B | |
| Boldine SCHEMBL30184400 | 0.85 | ALDH1A1 (1.00) | DRD1DRD2HTR2AHTR7HTR2B | |
| Boldine SCHEMBL177550 | 0.85 | ALDH1A1 (1.00) | DRD1DRD2HTR2AHTR7HTR2B | |
| Boldine SCHEMBL7387149 | 0.85 | ALDH1A1 (1.00) | DRD1DRD2HTR2AHTR7HTR2B | |
| Predicentrine SCHEMBL4410538 | 0.85 | ALDH1A1 (0.91) | DRD1DRD2HTR2AHTR7HTR2B | |
| Boldine SCHEMBL177549 | 0.85 | ALDH1A1 (1.00) | DRD1DRD2HTR2AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294715-B2 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | LOTUS PHARMACEUTICAL CO., LTD. (TW) | 2007-11-13 | — | — | US | disclosed |
| US-20060211723-A1 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | LOTUS PHARMACEUTICAL CO., LTD. (TW) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211723-A1 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | OGFRL1, THOP1, APOL1 | DRD1 695/4885DRD2 858/4885HTR2A 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.