Sugi Predict

Sugi Predict / Compounds / Ether

Ether

Ether

SCHEMBL566067

C=CCNc1c(O)cccc1-c1cccc(O)c1NCC=C.CCOCC

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MITF O75030 1/20 0.34
▸ NSD2 O96028 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CASP3 P42574 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ SENP8 Q96LD8 1/20 0.34
▸ SENP7 Q9BQF6 1/20 0.34
▸ SENP6 Q9GZR1 1/20 0.34
▸ RAB9A P51151 3/20 0.33
▸ CA1 P00915 3/20 0.33
▸ CA9 Q16790 3/20 0.33
▸ HPGD P15428 2/20 0.33
▸ CA12 O43570 2/20 0.33
▸ CA2 P00918 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565762 0.89 ALDH1A1 (0.40) MAPTKMT2AMEN1HIF1AL3MBTL1
SCHEMBL566068 0.82 KMT2A (0.39) MAPTKMT2AMEN1HIF1AL3MBTL1
Ether SCHEMBL566237 0.79 MAPT (0.41) MAPTKMT2AMEN1HIF1AL3MBTL1
SCHEMBL565941 0.72 ALDH1A1 (0.36) MAPTKMT2AMEN1HIF1AL3MBTL1
Ether SCHEMBL564674 0.70 MAPT (0.39) MAPTL3MBTL1ALDH1A1LMNAHTT
Ether SCHEMBL565588 0.70 GABRA1 (0.40) MAPTL3MBTL1ALDH1A1LMNARAB9A
SCHEMBL564293 0.69 GAA (0.42) MAPTKMT2AMEN1HIF1AL3MBTL1
Ether SCHEMBL5662397 0.68 ALDH1A1 (0.46) MAPTKMT2AMEN1HIF1AL3MBTL1
SCHEMBL565303 0.67 ALDH1A1 (0.40) MAPTKMT2AMEN1HIF1AL3MBTL1
Pyrogallol SCHEMBL3175241 0.66 CA1 (0.60) MAPTALDH1A1LMNARAB9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 MAPT 3886/4885KMT2A 2278/4885MEN1 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.