Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707747 | 0.87 | TDP1 (0.40) | — | |
| SCHEMBL6880850 | 0.78 | TAS1R3 (0.49) | BCHE | |
| SCHEMBL5664254 | 0.77 | TK1 (0.46) | TK1BCHERNASE1TYMP | |
| SCHEMBL6875722 | 0.75 | TYMP (0.41) | BCHETYMP | |
| SCHEMBL5666253 | 0.70 | RNASE1 (0.43) | TK1BCHERNASE1TYMPTK2 | |
| SCHEMBL11981102 | 0.70 | TK1 (0.44) | TK1BCHERNASE1NT5MTYMP | |
| SCHEMBL14946306 | 0.70 | TK1 (0.44) | TK1BCHERNASE1NT5MTYMP | |
| SCHEMBL21332204 | 0.70 | TK1 (0.42) | TK1BCHERNASE1NT5MTYMP | |
| SCHEMBL2770785 | 0.70 | TK1 (0.46) | TK1RNASE1TYMPTK2 | |
| SCHEMBL2770788 | 0.70 | TK1 (0.46) | TK1RNASE1TYMPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403566-B1 | CONFORMATIONALLY LOCKED; ANTIVIRAL, ANTICANCER, STABILITY TO CELLULAR NUCLEASES AND STRONG BINDING AFFINITY TO NUCLEIC ACID TARGETS. | ICN PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | disclosed |