Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL4902639 | 0.95 | TSHR (0.33) | TSHR | |
| SCHEMBL27573213 | 0.83 | TSHR (0.34) | TSHR | |
| SCHEMBL9634740 | 0.69 | LMNA (0.41) | TSHRL3MBTL1APEX1BLM | |
| SCHEMBL4132081 | 0.68 | CA12 (0.39) | — | |
| SCHEMBL9182492 | 0.67 | L3MBTL1 (0.43) | TSHRL3MBTL1 | |
| SCHEMBL27786269 | 0.67 | TSHR (0.36) | TSHRL3MBTL1APEX1BLM | |
| Succinamide SCHEMBL7647282 | 0.67 | TSHR (0.36) | TSHRL3MBTL1APEX1BLM | |
| SCHEMBL29385194 | 0.66 | ALDH1A1 (0.36) | BLM | |
| SCHEMBL23618003 | 0.65 | MAPT (0.46) | TSHRL3MBTL1 | |
| SCHEMBL122496 | 0.65 | KDM4E (0.38) | TSHRL3MBTL1APEX1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027016-A4 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE CLOSURE OF RETINAL BREAKS | UNIV CALIFORNIA (US) | 2006-03-08 | — | — | EP | disclosed |
| US-20030223957-A1 | Biodegradable PEG based polymer formulations in ocular applications | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-12-04 | — | — | US | disclosed |
| WO-2003086305-A2 | BIODEGRADABLE PEG-BASED POLYMER FORMULATIONS IN OCULAR APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6475508-B1 | Methods and pharmaceutical compositions for the closure of retinal breaks | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-11-05 | — | — | US | disclosed |
| US-6149931-A | Methods and pharmaceutical compositions for the closure of retinal breaks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-11-21 | — | — | US | disclosed |
| EP-1027016-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE CLOSURE OF RETINAL BREAKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021512-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE CLOSURE OF RETINAL BREAKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-05-06 | — | — | WO | disclosed |