Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242766 | 1.00 | RAB9A (0.43) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL8124050 | 0.96 | RAB9A (0.44) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL10937320 | 0.89 | GPR35 (0.38) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL8520275 | 0.79 | ALDH1A1 (0.33) | RECQLALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL8346779 | 0.79 | ALDH1A1 (0.33) | RECQLALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL7755252 | 0.79 | EPHX1 (0.32) | TDP1L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL7744026 | 0.79 | ALDH1A1 (0.33) | RECQLALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL707743 | 0.76 | MEN1 (0.42) | RAB9ANPC1ALDH1A1TDP1KMT2A | |
| SCHEMBL1582160 | 0.76 | MEN1 (0.42) | RAB9ANPC1ALDH1A1TDP1KMT2A | |
| SCHEMBL8603750 | 0.76 | MEN1 (0.42) | RAB9ANPC1ALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708922-B1 | IDENTIFICATION OF LIGANDS BY SELECTIVE AMPLIFICATION OF CELLS TRANSFECTED WITH RECEPTORS | ACADIA PHARM INC (US) | 1999-03-10 | — | — | EP | claimed |
| JP-11315101-A | — | — | None | — | — | JP | disclosed |
| JP-11315092-A | — | — | None | — | — | JP | disclosed |
| US-20150293076-A1 | Cellular Reprogramming for Product Optimization | BOLT THREADS, INC. | 2015-10-15 | — | — | US | disclosed |
| WO-2014066374-A1 | CELLULAR REPROGRAMMING FOR PRODUCT OPTIMIZATION | REFACTORED MATERIALS, INC. (US) | 2014-05-01 | — | — | WO | disclosed |
| CN-102695955-A | Assays for detecting anti-TNF drugs and autoantibodies | PROMETHEUS LAB INC | 2012-09-26 | — | — | CN | disclosed |
| CN-101180530-B | Method of analyzing biochemical substance, analyzing reagent kit and analyzer | HITACHI CHEMICAL CO LTD | 2011-11-09 | — | — | CN | disclosed |
| CN-101180530-A | Method of analyzing biochemical | HITACHI CHEMICAL CO LTD (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-101160525-A | Genetic code increase of non-natural active amino acid | SCRIPPS RESEARCH INST (US) | 2008-04-09 | — | — | CN | disclosed |
| EP-1468098-A4 | METHOD OF INHIBITING PATHOGENICITY OF INFECTIOUS AGENTS | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-04-12 | — | — | EP | disclosed |
| US-5118611-A | Useful for diagnostic, imaging treatment of cancer involving antibody binding interaction with marker | ADEZA BIOMEDICAL CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| US-5096830-A | Determination of fetal fibronectin presence in vaginal secretion | ADEZA BIOMEDICAL CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-5079171-A | Blood analysis, antibodies, competition or sandwich immunoassay | ADEZA BIOMEDICAL CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0232816-B1 | HETEROGENEOUS SPECIFIC BINDING ASSAY EMPLOYING AN AGGREGATABLE BINDING REAGENT | MILES INC. (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0387027-A2 | Endometriosis diagnosis methods and reagents | ADEZA BIOMEDICAL CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0359274-A2 | Pregnancy induced hypertension and eclampsia immunossay and reagents | ADEZA BIOMEDICAL CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0352722-A2 | Adenocarcinoma antigen binding methods and reagents | Smith, Lloyd H. (US) | 1990-01-31 | — | — | EP | disclosed |
| EP-0316919-A2 | Vaginal sample test and reagents | ADEZA BIOMEDICAL CORPORATION (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4772550-A | Heterogeneous specific binding assay employing an aggregatable binding reagent | MILES INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4560648-A | CONJUGATED THROUGH THIO GROUP OF B-GALACTOSIDASE | SYNTEX (U.S.A.) INC. (US) | 1985-12-24 | — | — | US | disclosed |