Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346779 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1ADRA2BPTGS1LMNA | |
| SCHEMBL8520275 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1ADRA2BPTGS1LMNA | |
| SCHEMBL7755252 | 0.83 | EPHX1 (0.32) | TDP1LMNAL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL3512233 | 0.79 | LMNA (0.35) | ALDH1A1TDP1LMNAL3MBTL1RECQL | |
| SCHEMBL5822045 | 0.79 | LMNA (0.35) | ALDH1A1TDP1LMNAL3MBTL1RECQL | |
| SCHEMBL1377219 | 0.79 | LMNA (0.35) | ALDH1A1TDP1LMNAL3MBTL1RECQL | |
| SCHEMBL20242766 | 0.79 | RAB9A (0.43) | ALDH1A1TDP1LMNAL3MBTL1RECQL | |
| SCHEMBL5664768 | 0.79 | RAB9A (0.43) | ALDH1A1TDP1LMNAL3MBTL1RECQL | |
| SCHEMBL9191589 | 0.78 | APP (0.35) | ALDH1A1TDP1LMNAL3MBTL1USP2 | |
| SCHEMBL7913872 | 0.78 | APP (0.35) | ALDH1A1TDP1LMNAL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000796-A2 | GLYCOSYLTRANSFERASES OF HELICOBACTER PYLORI | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2001-01-04 | — | — | WO | disclosed |