Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309425 | 0.76 | L3MBTL1 (0.40) | L3MBTL1POLBCA12CA1CA2 | |
| SCHEMBL6309420 | 0.76 | L3MBTL1 (0.40) | L3MBTL1POLBCA12CA1CA2 | |
| SCHEMBL5663296 | 0.75 | L3MBTL1 (0.40) | L3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL6307242 | 0.75 | L3MBTL1 (0.40) | L3MBTL1POLBSMN1; SMN2MAPTGAA | |
| SCHEMBL5662451 | 0.75 | L3MBTL1 (0.40) | L3MBTL1HMGCRKMT2AMAPTCYP1A2 | |
| SCHEMBL6306977 | 0.75 | L3MBTL1 (0.40) | L3MBTL1POLBCA12CA1CA2 | |
| SCHEMBL6305868 | 0.75 | L3MBTL1 (0.40) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL5663721 | 0.74 | FDPS (0.39) | L3MBTL1FDPSKMT2AGAACYP1A2 | |
| SCHEMBL14665252 | 0.73 | ALDH1A1 (0.41) | ALOX5KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL6307777 | 0.73 | L3MBTL1 (0.38) | L3MBTL1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060205692-A1 | 1,1-and 1,2-Bisphosphonates as apoliprotein e modulators | MONTES IMBER F | 2006-09-14 | — | — | US | disclosed |
| EP-1506208-A4 | 1,1- AND 1,2-BISPHOSPHONATES AS APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| EP-1506208-A2 | 1,1- AND 1,2-BISPHOSPHONATES AS APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094851-A2 | 1,1- AND 1,2-BISPHOSPHONATES AS APOLIPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205692-A1 | 1,1-and 1,2-Bisphosphonates as apoliprotein e modulators | APOB, APOL1, HDLBP | L3MBTL1 1504/4885HMGCR 174/4885POLB 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.