SCHEMBL5666571

SCHEMBL5666571

C#Cc1ccc(C(=O)O)c(C(C)(C)c2cc(C#C)ccc2C(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.39
RARG P13631 1/20 0.39
PTGS2 P35354 2/20 0.38
HNF4A P41235 1/20 0.38
PTGS1 P23219 1/20 0.38
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
TAS2R14 Q9NYV8 1/20 0.36
CYP1A2 P05177 1/20 0.35
CSNK2A1 P68400 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RXRB P28702 1/20 0.35
FFAR1 O14842 1/20 0.35
SELL P14151 1/20 0.34
SELP P16109 1/20 0.34
MEN1 O00255 1/20 0.34
PDE4A P27815 1/20 0.34
BLVRB P30043 1/20 0.34
KDR P35968 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746253 0.88 PTGS1 (0.37) RARBRARGPTGS2HNF4APTGS1
SCHEMBL22834192 0.82 TAS2R14 (0.45) PTGS2HNF4APTGS1ADRA2BADRA2C
SCHEMBL5669819 0.79 HNF4A (0.63) RARBRARGHNF4AFFAR1HTT
SCHEMBL541999 0.79 HNF4A (0.43) PTGS2HNF4APTGS1ADRA2BADRA2C
SCHEMBL1978850 0.78 RXRB (0.44) RARBPTGS2PTGS1CYP1A2CSNK2A1
Hydrochloric Acid SCHEMBL6732842 0.77 HNF4A (0.42) PTGS2HNF4APTGS1ADRA2BADRA2C
SCHEMBL2745941 0.77 CYP1A2 (0.41) PTGS2HNF4APTGS1ADRA2BADRA2C
SCHEMBL2620550 0.76 ALDH1A1 (0.41) PTGS2HNF4APTGS1ADRA2BADRA2C
SCHEMBL2536166 0.76 HNF4A (0.62) PTGS2HNF4ACSNK2A1TDP1MEN1
SCHEMBL7615611 0.76 ALDH1A1 (0.55) HNF4ATDP1SELLSELPMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed