Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.33 |
| ▸ | CNR1 | P21554 | 9/20 | 0.33 |
| ▸ | GPR18 | Q14330 | 3/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834873 | 0.98 | CNR2 (0.33) | CNR2CNR1GPR18GPR55ESR2 | |
| SCHEMBL5835163 | 0.92 | ACSS2 (0.38) | CNR2CNR1GPR18GPR55ESR2 | |
| SCHEMBL768936 | 0.91 | ACSS2 (0.34) | CNR2CNR1GPR18GPR55ESR2 | |
| SCHEMBL5835358 | 0.90 | ACSS2 (0.34) | CNR2CNR1GPR18GPR55ACSS2 | |
| SCHEMBL7143972 | 0.90 | ACSS2 (0.34) | CNR2CNR1GPR18GPR55ACSS2 | |
| SCHEMBL5668744 | 0.88 | CNR2 (0.33) | CNR2POLBACSS2 | |
| SCHEMBL5834568 | 0.87 | POLB (0.35) | CNR2CNR1ESR2POLBACSS2 | |
| SCHEMBL224924 | 0.87 | CNR1 (0.38) | CNR2CNR1GPR18GPR55POLB | |
| SCHEMBL7142426 | 0.87 | CNR2 (0.37) | CNR2CNR1GPR18GPR55POLB | |
| SCHEMBL10484223 | 0.86 | CNR2 (0.37) | CNR2CNR1GPR18GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | claimed |
| US-7074906-B2 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1175467-B1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | disclosed |
| US-20050053562-A1 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SPECIALTY CHEMICALS CORP. | 2005-03-10 | — | — | US | disclosed |
| US-6815550-B2 | DIAZOTIZING A 5-PERFLUOROALKYL-O-NITROANILINE WITH SULFURIC ACID AND ALKALI METAL NITRITE OR NITROSYLSULFURIC ACID; COUPLING WITH A PHENOL; AND REDUCING THE MONOAZOBENZENE INTERMEDIATE TO THE CORRESPONDING 2H-BENZOTRIAZOLE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-11-09 | — | — | US | disclosed |
| EP-1451254-A1 | ORGANIC SOLVENT-FREE PROCESS FOR THE PREPARATION OF 2-(2-NITROPHENYLAZO)PHENOLS | Ciba SC Holding AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| US-6605727-B2 | Processes for the preparation of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-20030130524-A1 | Processes for the preparation of benzotriazole UV absorbers | WOOD MERVIN G (US) | 2003-07-10 | — | — | US | disclosed |
| US-20030120083-A1 | Processes for the preparation of benzotriazole UV absorbers | WOOD MERVIN G (US) | 2003-06-26 | — | — | US | disclosed |
| WO-2003048257-A1 | ORGANIC SOLVENT-FREE PROCESS FOR THE PREPARATION OF 2-(2-NITROPHENYLAZO)PHENOLS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-12 | — | — | WO | disclosed |
| EP-1144391-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-20010007886-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2001-07-12 | — | — | US | disclosed |
| US-6187845-B1 | LAMINATION OR MULTILAYER STRUCTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-13 | — | — | US | disclosed |
| US-6166218-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000066676-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000043376-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |
| US-5977219-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050053562-A1 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | HPD, CYP8B1, CYP3A4 | CNR2 1601/4885CNR1 2074/4885GPR18 4036/4885 |
| US-20030120083-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | CNR2 2346/4885CNR1 2110/4885GPR18 2440/4885 |
| US-20030130524-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | CNR2 2346/4885CNR1 2110/4885GPR18 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.