SCHEMBL7142426

SCHEMBL7142426

CCCCCC(C)(C)c1cc(-c2ccccc2)c(O)c(-n2nc3ccc(S(=O)(=O)c4ccccc4)cc3n2)c1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 16/20 0.37
CNR1 P21554 15/20 0.37
GPR18 Q14330 2/20 0.33
GPR55 Q9Y2T6 2/20 0.33
TRPV1 Q8NER1 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7142425 0.88 POLB (0.33) CNR2POLB
SCHEMBL5668745 0.87 CNR2 (0.33) CNR2CNR1GPR18GPR55POLB
SCHEMBL5643806 0.86 CNR2 (0.41) CNR2CNR1GPR18GPR55
SCHEMBL5834873 0.85 CNR2 (0.33) CNR2CNR1GPR18GPR55POLB
SCHEMBL7149445 0.84 CNR1 (0.39) CNR2CNR1
SCHEMBL7148633 0.82 CNR2 (0.38) CNR2CNR1GPR18GPR55
SCHEMBL7588136 0.81 CNR1 (0.44) CNR2CNR1GPR18GPR55POLB
SCHEMBL5835163 0.79 ACSS2 (0.38) CNR2CNR1GPR18GPR55POLB
SCHEMBL768936 0.78 ACSS2 (0.34) CNR2CNR1GPR18GPR55POLB
SCHEMBL5835358 0.77 ACSS2 (0.34) CNR2CNR1GPR18GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515051-B2 Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-04 US disclosed
US-6458872-B1 FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-01 US disclosed
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-07-25 US disclosed
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-05-30 US disclosed
US-6262151-B1 FOR AUTOMOTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 US disclosed
US-20010007886-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2001-07-12 US disclosed
US-6166218-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 US disclosed
US-5977219-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability TERT, AHR, ARNT CNR2 2562/4885CNR1 2980/4885GPR18 2527/4885
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability TERT, AHR, ARNT CNR2 2562/4885CNR1 2980/4885GPR18 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.