SCHEMBL5669173

SCHEMBL5669173

O=C(O)c1cccc(C(c2cccc(C(=O)O)c2C#Cc2cccc(-c3ccccc3)c2)(C(F)(F)F)C(F)(F)F)c1C#Cc1cccc(-c2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 8/20 0.43
PTPN6 P29350 7/20 0.43
PTPN22 Q9Y2R2 7/20 0.43
PTPN1 P18031 7/20 0.43
PTPRC P08575 6/20 0.43
PTPN2 P17706 6/20 0.43
PTPN9 P43378 6/20 0.43
DUSP3 P51452 6/20 0.43
PTPRG P23470 3/20 0.43
ACP1 P24666 3/20 0.43
PTPN7 P35236 3/20 0.43
PTPN13 Q12923 3/20 0.43
DUSP22 Q9NRW4 3/20 0.43
CDC14A Q9UNH5 3/20 0.43
EPM2A O95278 2/20 0.43
HNF4A P41235 3/20 0.40
FABP4 P15090 1/20 0.39
XDH P47989 1/20 0.39
SLC22A12 Q96S37 1/20 0.39
ACMSD Q8TDX5 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5669824 0.85 HNF4A (0.41) PTPN11PTPN6PTPN22PTPN1PTPRC
SCHEMBL5669133 0.84 HNF4A (0.50) PTPN11PTPN6PTPN22PTPN1PTPRC
SCHEMBL5667768 0.80 FABP4 (0.40) PTPN11PTPN22PTPRCPTPN9HNF4A
SCHEMBL2747181 0.76 HNF4A (0.40) PTPN11PTPN6PTPN22PTPN1PTPRC
SCHEMBL2747049 0.74 HNF4A (0.58) PTPN11PTPN1HNF4AAKR1C2AKR1C1
SCHEMBL5666568 0.74 KCNH2 (0.41) PTPN11PTPN6PTPN22PTPN1PTPRC
SCHEMBL5669586 0.73 HNF4A (0.44) PTPN11PTPN6PTPN22PTPN1PTPRC
SCHEMBL5668837 0.72 HNF4A (0.49) PTPN11PTPN6PTPN22PTPN1PTPRC
SCHEMBL30023558 0.71 ALDH1A1 (0.52) FABP4
SCHEMBL3870690 0.71 ALDH1A1 (0.52) FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed