Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649406 | 0.75 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL5010686 | 0.72 | HNF4A (0.48) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL5008857 | 0.72 | HNF4A (0.48) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL4071673 | 0.71 | HNF4A (0.47) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL5010723 | 0.69 | HNF4A (0.53) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL2333980 | 0.69 | ALDH1A1 (0.56) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL30618783 | 0.69 | ALDH1A1 (0.56) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL11591876 | 0.69 | HNF4A (0.46) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL9140507 | 0.69 | RAB9A (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL3806469 | 0.68 | HNF4A (0.53) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1247142-A4 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS | LEXMARK INT INC (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-1247142-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS | Lexmark International, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6350553-B2 | CHARGE TRANSFER LAYER; CHARGE GENERATING LAYER | LEXMARK INTERNATIONAL, INC. | 2002-02-26 | — | — | US | disclosed |
| US-20010023047-A1 | Electrophotographic photoconductors comprising polyaryl ethers | LEXMARK INTERNATIONAL, INC. | 2001-09-20 | — | — | US | disclosed |
| WO-2001051995-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS | LEXMARK INTERNATIONAL, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| US-6232025-B1 | CHARGE TRANSFER AND CHARGE GENERATING LAYERS | LEXMARK INTERNATIONAL, INC. | 2001-05-15 | — | — | US | disclosed |