Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 6/20 | 0.49 |
| ▸ | GRM8 | O00222 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
| ▸ | GRM6 | O15303 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56061 | 0.84 | GRM4 (0.58) | GRM4GRM8CETPGRM6FOLH1 | |
| SCHEMBL56051 | 0.83 | FOLH1 (0.46) | GRM4GRM8CETPGRM6FOLH1 | |
| SCHEMBL56601 | 0.83 | SLC1A5 (0.46) | GRM4GRM8RAB9ACETPGRM6 | |
| SCHEMBL57236 | 0.82 | GRM8 (0.62) | GRM4GRM8RAB9ACETPGRM6 | |
| Glufosinate SCHEMBL28207831 | 0.76 | GRM4 (0.59) | GRM4GRM8GRM6 | |
| SCHEMBL7412848 | 0.75 | MMP12 (0.56) | GRM4 | |
| SCHEMBL56613 | 0.74 | CTSS (0.49) | — | |
| SCHEMBL56343 | 0.74 | GRM4 (0.57) | GRM4GRM8RAB9ACETPGRM6 | |
| SCHEMBL57177 | 0.74 | SLC7A5 (0.47) | GRM4GRM8CETPGRM6FOLH1 | |
| SCHEMBL56728 | 0.74 | GRM4 (0.46) | GRM4GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137446-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE | TRUSTEES OF BOSTON UNIVERSITY (US) | 2008-11-13 | — | — | WO | claimed |
| US-8129557-B2 | Phosphonic acid diester derivative and method for producing thereof | Nagai, Kazuhiro (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | HIRATAKE, GOU (JP) | 2009-06-25 | — | — | US | disclosed |
| WO-2008137446-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE | TRUSTEES OF BOSTON UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | PPA1, G6PD, PHOSPHO1 | GRM4 4122/4885GRM8 4595/4885RAB9A 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.