SCHEMBL5673134

SCHEMBL5673134

O=C(O)n1nnnc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.52
HSD11B1 P28845 2/20 0.50
ALDH1A1 P00352 5/20 0.46
TSHR P16473 2/20 0.46
KMT2A Q03164 1/20 0.45
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
LMNA P02545 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HDAC6 Q9UBN7 1/20 0.44
PTGS2 P35354 2/20 0.43
PKM P14618 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
FAAH O00519 1/20 0.42
HPGD P15428 1/20 0.41
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TRPV1 Q8NER1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12781922 0.82 MGLL (0.51) MGLLHSD11B1ALDH1A1TSHRPOLB
SCHEMBL31219218 0.81 MGLL (0.36) MGLLHSD11B1ALDH1A1LMNAFAAH
SCHEMBL4666990 0.75 KMT2A (0.52) HSD11B1ALDH1A1TSHRKMT2APOLB
SCHEMBL31219219 0.75 HDAC6 (0.36) MGLLHSD11B1ALDH1A1HDAC6HPGD
SCHEMBL7795144 0.74 ALDH1A1 (0.50) MGLLHSD11B1ALDH1A1TSHRKMT2A
SCHEMBL28402481 0.73 MGLL (0.41) MGLLHSD11B1ALDH1A1TSHRKMT2A
SCHEMBL5966693 0.73 ALDH1A1 (0.74) HSD11B1ALDH1A1TSHRPOLBHTT
SCHEMBL8947286 0.72 PTGS2 (0.46) MGLLHSD11B1ALDH1A1TSHRKMT2A
Urea SCHEMBL28915393 0.72 PTGS2 (0.64) ALDH1A1TSHRKMT2APOLBHTT
SCHEMBL9568787 0.72 HSD11B1 (0.46) MGLLHSD11B1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190085208-A1 POLISHING COMPOSITION, METHOD FOR PRODUCING SAME, POLISHING METHOD, AND METHOD FOR PRODUCING SUBSTRATE FUJIMI INCORPORATED (JP) 2019-03-21 US disclosed
US-7033742-B2 Method of photothermographic imaging for transmission electron microscopy EASTMAN KODAK COMPANY (US) 2006-04-25 US disclosed
US-20060022133-A1 METHOD OF PHOTOTHERMOGRAPHIC IMAGING FOR TRANSMISSION ELECTRON MICROSCOPY EASTMAN KODAK COMPANY 2006-02-02 US disclosed
EP-1315036-A1 Photothermographic systems comprising passivated organic silver salts EASTMAN KODAK COMPANY (US) 2003-05-28 EP disclosed
US-6497999-B1 ORGANIC ADSORBATE THAT BLOCKS THE SURFACE OF THE ORGANIC SILVER SALT OR LIGAND TO IMPROVE RAW STOCK SPEED, STORAGE STABILITY; SPECTRAL SENSITIZING DYE EASTMAN KODAK COMPANY 2002-12-24 US disclosed