Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14386990 | 0.95 | ALOX15 (0.45) | F2F10TP53POLBTHRB | |
| SCHEMBL5034766 | 0.93 | F2 (0.50) | F2F10TP53POLBTHRB | |
| SCHEMBL5032872 | 0.93 | F2 (0.50) | F2F10TP53POLBTHRB | |
| SCHEMBL5032864 | 0.92 | F2 (0.49) | F2F10TP53POLBTHRB | |
| SCHEMBL6298871 | 0.92 | F2 (0.49) | F2F10TP53POLBTHRB | |
| SCHEMBL5027947 | 0.90 | F2 (0.56) | F2F10TP53POLBTHRB | |
| SCHEMBL5674694 | 0.89 | HDAC6 (0.48) | KDM4EALDH1A1HPGDL3MBTL1HDAC6 | |
| SCHEMBL5030384 | 0.89 | CYP4A11 (0.52) | F2F10TP53POLBTHRB | |
| SCHEMBL5044528 | 0.88 | TBXAS1 (0.47) | F2F10TP53POLBTHRB | |
| SCHEMBL6301115 | 0.86 | TP53 (0.49) | F2F10TP53POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148240-B2 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2006-12-12 | — | — | US | disclosed |
| US-6949583-B2 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same | SANOFI-SYNTHELABO (FR) | 2005-09-27 | — | — | US | disclosed |
| US-6946483-B2 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2005-09-20 | — | — | US | disclosed |
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI (FR) | 2004-01-15 | — | — | US | disclosed |
| US-20030225100-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same | SANOFI (FR) | 2003-12-04 | — | — | US | disclosed |
| US-20030187060-A1 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | SANOFI (FR) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT1 | F2 689/4885F10 1627/4885TP53 4581/4885 |
| US-20030225100-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same | NR2C2, NR4A2, NR5A2 | F2 2788/4885F10 3807/4885TP53 4075/4885 |
| US-20030187060-A1 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT2 | F2 802/4885F10 1440/4885TP53 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.